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Updated: Jul 5, 2026

Anterior Cervical Discectomy and Fusion in the Ovine Model

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Published on: October 5, 2009

En coup de sabre accompanied by pachydermoperiostosis: a case report.

M Ozdemir¹, S Yildirim, I Mevlitoğlu

¹Department of Dermatology, Meram Medical Faculty, Selçuk University, Konya, Turkey. mustafaozdemir@yahoo.com

Clinical and Experimental Rheumatology

|June 5, 2007

Summary

Scleroderma en coup de sabre, a localized scleroderma variant, co-occurred with pachydermoperiostosis in a young female. This rare association highlights potential shared pathways in connective tissue disorders.

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Area of Science:

Dermatology
Genetics
Rheumatology

Background:

Scleroderma en coup de sabre is a localized scleroderma variant.
Pachydermoperiostosis is a rare genetic disorder causing skin and bone changes.

Observation:

A 21-year-old female presented with scleroderma en coup de sabre and pachydermoperiostosis.
The patient had a family history of pachydermoperiostosis in her sister.
Diagnosis was confirmed via clinical examination, histology, and X-ray.

Findings:

Scleroderma en coup de sabre involves connective tissue fibrosis.
Pachydermoperiostosis is a hypertrophic process with periosteal and skin changes.
This case details the coexistence of these two distinct disorders.

Implications:

The co-occurrence suggests potential shared genetic or etiological factors.
Further research may elucidate underlying mechanisms linking these conditions.
Understanding this association can improve diagnosis and management of rare connective tissue diseases.