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Related Experiment Video

Updated: Jul 14, 2026

Laparoscopic S7 Hepatectomy with Positive Fluorescence Staining

Laparoscopic S7 Hepatectomy with Positive Fluorescence Staining

Published on: May 9, 2025

The patient with unexplained elevated serum liver enzymes.

Axel Holstege¹, Peter Zolinski, Ludwig Woidy

¹Medizinische Klinik 1, Klinikum Landshut, Robert-Koch-Str. 1, 84034 Landshut, Germany. med-klinikl@klinikum-landshut.de

Best Practice & Research. Clinical Gastroenterology

|June 5, 2007

Summary

This case study highlights a rare instance of autoimmune pancreatitis causing sclerosing cholangitis. Prompt diagnosis and immunosuppressive therapy led to complete recovery in a female patient.

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Last Updated: Jul 14, 2026

Laparoscopic S7 Hepatectomy with Positive Fluorescence Staining

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Inducing Acute Liver Injury in Rats via Carbon Tetrachloride (CCl4) Exposure Through an Orogastric Tube

Inducing Acute Liver Injury in Rats via Carbon Tetrachloride (CCl₄) Exposure Through an Orogastric Tube

Published on: April 28, 2020

Area of Science:

Gastroenterology
Hepatology
Immunology

Background:

Elevated liver enzymes aid in classifying liver diseases.
Extrahepatic cholestasis can stem from bile duct strictures and pancreatic lesions.

Purpose of the Study:

To present a challenging case of diagnosing sclerosing cholangitis secondary to autoimmune pancreatitis.
To discuss diagnostic approaches for complex liver and pancreatic diseases.

Main Methods:

Clinical presentation of a female patient with extrahepatic cholestasis.
Diagnostic procedures including surgical laparotomy and bioptic sampling.
Microscopic examination of bile duct, lymph node, and pancreatic tissue.

Main Results:

Diagnosis of sclerosing cholangitis in systemic autoimmune pancreatitis confirmed via biopsy.
Extensive biliary and pancreatic scarring with inflammatory infiltrates observed.
Complete patient recovery following treatment with prednisone and azathioprine.

Conclusions:

Autoimmune pancreatitis can manifest as sclerosing cholangitis, posing diagnostic challenges.
Multidisciplinary diagnostic tools are crucial for complex hepatobiliary and pancreatic conditions.
Immunosuppressive therapy is effective in managing this condition.