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Extremely elevated serum CA-125 level as a result of unruptured unilateral endometrioma: the highest value reported
Korhan Kahraman1, Irem Ozguven, Mete Gungor
1Department of Obstetrics and Gynecology, Ankara University School of Medicine, Ankara, Turkey. korhankahraman@hotmail.com
Objective:
To present a case of a unilateral endometrioma with extremely elevated serum CA-125 levels.
Design:
Case report.
Setting:
University hospital.
Patient(S):
A 25-year-old woman with left adnexal mass and extremely elevated serum CA-125 level, 7,900 U/mL, underwent laparoscopy. There were unilateral endometrioma and stage IV endometriosis.
Intervention(S):
Laparoscopic excision of the endometrioma, unilateral salpingectomy, adhesiolysis, ablation of endometriotic foci, and partial omentectomy were performed, and histopathologic results confirmed the diagnosis of endometriosis.
Main Outcome Measure(S):
Extremely elevated serum CA-125 levels and unruptured ovarian endometrioma.
Result(S):
On the second, sixth, and 13th days of the menstrual period, serum CA-125 levels were 7,900 U/mL, 1,577 U/mL, and 627 U/mL, respectively. On the third postoperative day serum CA-125 level was 56 U/mL.
Conclusion(S):
Ovarian endometrioma and advanced endometriosis may be associated with extremely elevated serum CA-125 levels. For this reason ovarian endometrioma should be considered with respect to differential diagnosis of reproductive-age women presenting with an ovarian mass even if it resembles an ovarian malignancy.
