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[Hypoglycemia secondary to transitory hyperinsulinism in infancy: a case report]
G Bonora1, L Castelli, M Nedbal
1Divisione di Pediatria, Ospedale Vizzolo Predabissi, Milano, Italia.
Insights
This study details a nine-month-old infant with temporary hyperinsulinism successfully treated with diazoxide. The child experienced normal growth and neurological development after treatment cessation.
Area of Science:
- Pediatrics
- Neonatology
- Endocrinology
Background:
- Hyperinsulinism is a significant cause of hypoglycemia in infants.
- Transitory hyperinsulinism requires timely diagnosis and management.
Observation:
- A nine-month-old infant presented with symptoms of hyperinsulinism.
- The infant was treated with diazoxide, a common medication for this condition.
Findings:
- Diazoxide therapy was successful and discontinued at 21 months.
- Follow-up until 38 months showed normal growth and neurological development.
- The case highlights the successful management of transitory hyperinsulinism.
Implications:
- This case supports diazoxide as an effective treatment for transitory hyperinsulinism.
- Early intervention and treatment lead to favorable long-term outcomes.
- Further research into the causes of hyperinsulinism is warranted.
Abstract:
We refer about an infant with transitory hyperinsulinism who first developed symptoms at the age of nine month treated with diazoxide. The therapy was successfully discontinued at the age of twenty-one month. The follow-up until the age of 38 month revealed a normal growing up and a normal neurological development. The main cause of hypoglycaemia are discussed referring the different cases of hyperinsulinism of the recent literature.