Related Experiment Video
Updated: Jul 14, 2026

Non-Intubated Video-Assisted Thoracoscopic Surgery
Published on: May 26, 2023
[Time window for intubation after rocuronium administration during target-controlled infusion of propofol and
Miao-ning Gu1, Meng Wang, Zai-sheng Qin
1Department of Anesthesia, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Objective:
To define the ideal time window for intubation after rocuronium administration during target-controlled infusion (TCI) ofpropofol and sulfentanil.
Methods:
One hundred and twenty elective surgical patients (age range 18-55 years) were randomized into 4 groups (n=30) according to the intubation time after administration of the muscle relaxant. Patients with predicted difficult airway were excluded. General anesthesia was induced by TCI of propofol and sulfentanil. A senior anesthesiologist blinded for the randomization performed the intubations at 1, 2, 3, or 4 min after injection of rocuronium, and the vocal card visibility was evaluated upon full exposure of the vocal cord and the intubation conditions assessed according to Cooper's score.
Results:
The intubation conditions were excellent or good in all patients, but the vocal cord visibility at 2-4 min differed significantly from that at 1 min after rocuronium administration (P<0.01). Suppression of the neuromuscular function 1 min after rocuronium administration differed significantly from that at other time points (P<0.01).
Conclusion:
The condition of vocal cord can be more suitable for intubation at 2-4 min than at 1 min after rocuronium administration as the ideal time window for intubation during TCI of propofol and sulfentanil.
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