Does obsessive-compulsive personality disorder belong within the obsessive-compulsive spectrum?
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Updated: Jul 14, 2026

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
Naomi A Fineberg1, Punita Sharma, Thanusha Sivakumaran
1Postgraduate School of Medicine, University of Hertfordshire, Queen Elizabeth II Hospital, Welwyn Garden City, UK. kim.fox@hpt.nhs.uk
Abstract:
It has been proposed that certain Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Axis I disorders share overlapping clinical features, genetic contributions, and treatment response and fall within an "obsessive-compulsive" spectrum. Obsessive-compulsive personality disorder (OCPD) resembles obsessive-compulsive disorder (OCD) and other spectrum disorders in terms of phenomenology, comorbidity, neurocognition, and treatment response. This article critically examines the nosological profile of OCPD with special reference to OCD and related disorders. By viewing OCPD as a candidate member of the obsessive-compulsive spectrum, we gain a fresh approach to understanding its neurobiology, etiology, and potential treatments.
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