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Updated: Jul 14, 2026
10:57
Real-Time, Two-Color Stimulated Raman Scattering Imaging of Mouse Brain for Tissue Diagnosis
Published on: February 1, 2022
6450 nm wavelength tissue ablation using a nanosecond laser based on difference frequency mixing and stimulated Raman
G S Edwards1, R D Pearlstein, M L Copeland
1Free-Electron Laser Laboratory, Duke University, Durham, North Carolina 27708, USA. edwards@fel.duke.edu
Optics Letters
|June 5, 2007
Abstract:
A four-stage laser system was developed, emitting at a wavelength of 6450 nm with a 3-5 ns pulse duration, < or = 2 mJ pulse energy, and 1/2 Hz pulse repetition rate. The laser system successfully ablated rat brain tissue, where both the collateral damage and the ablation rate compare favorably with that previously observed with a Mark-III Free-Electron Laser.
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