Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Novel hormone "receptors".

Ilka Nemere1, Korry Hintze

  • 1Department of Nutrition and Food Sciences and the Center for Integrated Biosciences, Utah State University, Logan Utah, USA. Nemere@cc.usu.edu

Journal of Cellular Biochemistry
|June 5, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum: Diosgenin-induced cognitive enhancement in normal mice is mediated by 1,25D3-MARRS.

Scientific reports·2015
Same author

The 1,25D3 -MARRS receptor/PDIA3/ERp57 and lifespan.

Journal of cellular biochemistry·2014
Same author

Diosgenin-induced cognitive enhancement in normal mice is mediated by 1,25D₃-MARRS.

Scientific reports·2013
Same author

1α,25-dihydroxyvitamin D3 and resolvin D1 retune the balance between amyloid-β phagocytosis and inflammation in Alzheimer's disease patients.

Journal of Alzheimer's disease : JAD·2012
Same author

Diosgenin is an exogenous activator of 1,25D₃-MARRS/Pdia3/ERp57 and improves Alzheimer's disease pathologies in 5XFAD mice.

Scientific reports·2012
Same author

Role of the 1,25D3-MARRS receptor in the 1,25(OH)2D3-stimulated uptake of calcium and phosphate in intestinal cells.

Steroids·2012

Recent discoveries reveal novel protein receptors, including enzymes, for hormones like atrial natriuretic hormone and vitamin D. This review explores these new hormone receptor identifications and their implications.

Area of Science:

  • Endocrinology and Molecular Biology
  • Exploration of novel signaling pathways
  • Interdisciplinary approach linking biochemistry and physiology

Background:

  • Traditional understanding of hormone receptors was limited.
  • Emerging research identifies diverse proteins, including enzymes, functioning as hormone receptors.
  • This paradigm shift necessitates a re-evaluation of endocrine signaling.

Purpose of the Study:

  • To review and synthesize recent findings on novel hormone receptors.
  • To highlight enzymes and other proteins identified as receptors for various hormones.
  • To provide a comprehensive overview of the expanding landscape of hormone-receptor interactions.

Main Methods:

  • Literature review of recent scientific publications.

Related Experiment Videos

  • Analysis of studies reporting novel receptor identifications.
  • Synthesis of information on specific hormone-receptor pairs.

    • Main Results:

    • Identification of novel receptors for atrial natriuretic hormone, enterostatin, and hepcidin.
    • Characterization of new receptors for thyroid hormones, estradiol, and progesterone.
    • Documentation of newly discovered receptors for vitamin D metabolites 1,25(OH)(2)D(3) and 24,25(OH)(2)D(3).

    Conclusions:

    • Hormone receptor identification has significantly broadened beyond traditional G protein-coupled receptors and nuclear receptors.
    • Enzymes and other proteins represent a new class of hormone receptors.
    • This expanded understanding has profound implications for endocrinology and drug development.