[Ischemic stroke in young adults]
1Service de Neurologie, Hôpital Lariboisière, 2, rue Ambroise-Paré, Paris (75), France. france.woimant@lrb.aphp.fr
Insights
Ischemic strokes can occur in young adults due to various causes, with many cases remaining unexplained. While prognosis is generally good, long-term quality of life can be significantly impacted.
Area of Science:
- Neurology
- Vascular Medicine
- Epidemiology
Context:
- Ischemic strokes, though less common than in older populations, are a recognized clinical issue in young adults.
- Cerebral ischemia in younger individuals stems from diverse etiologies including arterial, cardiac, hematological, and genetic factors.
- A significant proportion, 30-50%, of ischemic stroke cases in young adults lack a definitive identified cause despite thorough investigation.
Purpose:
- To review the causes, diagnostic challenges, and prognosis of ischemic stroke in young adults.
- To highlight the impact of stroke sequelae on the quality of life for young patients and their families.
Summary:
- Multiple potential causes for ischemic stroke in young adults exist, including cervical dissection, arteriosclerosis, small-vessel disease, cardiac conditions, hematological disorders, and genetic predispositions.
- A substantial percentage of young adult ischemic stroke cases remain cryptogenic (unknown cause) after comprehensive diagnostic evaluation.
- The long-term outlook for young adults experiencing ischemic stroke is generally favorable, characterized by low mortality and recurrence rates.
Impact:
- Despite a better prognosis compared to the elderly, ischemic strokes in young adults can lead to persistent sequelae.
- These long-term consequences significantly affect the quality of life for affected individuals and their families, necessitating focused management and support.
Abstract:
Ischemic strokes are not exceptional in young adults. The causes of cerebral ischemia are multiple: arterial (cervical dissection, and to a lesser extent, arteriosclerosis, small-vessel occlusion ond vasculopathy) cardiac, hematological, genetic etc. Depending on the exhaustivity of the diagnostic work-up, 30 to 50% of cases have no clear cause. The long-term prognosis for the ischemic stroke in the young is better than in the elderly, mortality and recurrence rates are low. Many subjects suffer sequeloe that have on important impact on quality of life of the patients and their family
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