Related Experiment Video

Updated: Jul 14, 2026

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
06:57

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Published on: January 31, 2019

Sustained ventricular tachycardia in apical hypertrophic cardiomyopathy, midcavitary obstruction, and apical aneurysm

Neil K Sanghvi1, Cynthia M Tracy

  • 1Department of Medicine, George Washington University Hospital, Washington, DC. nsanghvi@gwu.edu

Pacing and Clinical Electrophysiology : PACE
|June 6, 2007
PubMed

Insights

Hypertrophic cardiomyopathy (HCM) can lead to apical aneurysms in about 1% of patients. This rare complication may increase cardiovascular death risk, necessitating defibrillator implantation for definitive therapy.

Area of Science:

  • Cardiology
  • Cardiovascular Medicine

Background:

  • Hypertrophic cardiomyopathy (HCM) affects 1:500 individuals.
  • A small percentage of HCM patients develop midcavitary obstruction and apical aneurysms.

Observation:

  • Presents a rare case of apical hypertrophic cardiomyopathy with aneurysm.
  • Etiology of apical aneurysm is unclear, possibly linked to fibrosis and ischemia.
  • Patients with apical aneurysms may face a higher cardiovascular death risk than general HCM patients.

Findings:

  • The lifetime risk of cardiovascular death in HCM is 2%.
  • Apical aneurysms might elevate this risk.
  • Medical therapy for this condition shows variable success.

Implications:

  • Definitive treatment involves automatic implantable cardioverter-defibrillator (AICD) implantation.
  • Highlights the need for further research into the etiology and management of apical HCM with aneurysms.

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