Related Experiment Video
Updated: Jul 14, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
Published on: August 11, 2008
[An analysis of the early diagnostic criteria for tuberculosis meningitis]
Yi Li1, Zhong Wang, Hou-li Wang
1The Emergency Department, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Objective:
To find a method for the early diagnosis of tuberculous meningitis (TM).
Methods:
Cases with the discharge diagnosis of TM during 1995 - 2004 ten years in the Peking Union Medical College Hospital were analyzed retrospectively. History of tuberculosis other sites of tuberculous infection, the findings of cerebrospinal fluid (CSF) and CSF culture result were studied.
Results:
16 of the 68 patients had past history of tuberculosis. During hospitalization 20 had pulmonary tuberculosis, while 9 had other sites of tuberculous infection. The rate of tuberculous infection aside from neurological system was 43%. The top 7 clinical manifestations were: coma, onset of the disease more than 5 days, lymphocyte predominant in CSF, glucose level in CSF 50% lower than that of blood, abnormal CT findings. Abnormal ocular fundi and proved tuberculosis of other sites.
Conclusions:
TM is often accompanied with tuberculous infection of other sites. Its diagnosis can not be relied mainly on the culture result of CSf. When 4 of the 7 above mentioned criteria are present, TM should be diagnosed and anti-tuberculosis therapy started.
Related Concept Videos
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Bacterial Meningitis I: Introduction
Viral Meningitis
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Bacterial Meningitis II: Pathophysiology
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
