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Related Experiment Video

Updated: Jul 14, 2026

Experimental Demyelination and Remyelination of Murine Spinal Cord by Focal Injection of Lysolecithin

Experimental Demyelination and Remyelination of Murine Spinal Cord by Focal Injection of Lysolecithin

Published on: March 26, 2015

Plasmapheresis for chronic inflammatory demyelinating polyradiculoneuropathy.

Man Mohan Mehndiratta¹, Avinash Chandra Singh

¹Professor of Neurology, #502, Academic Block, Department of Neurology, G.B. Pant Hospital, New Delhi 110002, India. mmehndi@hotmail.com

Current Allergy and Asthma Reports

|June 6, 2007

Summary

Plasma exchange offers significant short-term benefits for most patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). This review examines the effectiveness of plasmapheresis in managing CIDP symptoms and improving patient outcomes.

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Last Updated: Jul 14, 2026

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Published on: March 26, 2015

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Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination

Published on: September 12, 2016

Area of Science:

Neurology
Immunology
Clinical Trials

Background:

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a debilitating immune-mediated disorder.
CIDP presents with progressive or relapsing motor and sensory deficits, leading to significant disability.
The condition can have severe long-term consequences, including mortality.

Purpose of the Study:

To evaluate the efficacy of plasmapheresis as a treatment for CIDP.
To review existing evidence on the role of plasma exchange in managing CIDP patients.

Main Methods:

Systematic review of clinical trials and relevant literature.
Analysis of data on patient response to plasma exchange therapy.

Main Results:

Plasma exchange demonstrates significant short-term benefits in approximately two-thirds of CIDP patients.
Evidence suggests a positive impact on symptom management and functional recovery.

Conclusions:

Plasmapheresis is a valuable therapeutic option for short-term management of CIDP.
Further research may explore long-term efficacy and optimal treatment protocols.