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Updated: Jul 14, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
A clinicoradiologic analysis of symptomatic craniofacial fibro-osseous lesions
Naresh K Panda1, Pradipta K Parida, Ramesh Sharma
1Department of Otolaryngology-Head and Neck Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh-160012, India. npanda59@yahoo.com
Objective:
To outline the clinical and radiologic aspects of symptomatic craniofacial fibro-osseous lesions and to study the appropriate surgical management with follow-up results.
Study Design And Setting:
A retrospective review of 11 patients who underwent surgical treatment during 1985 to 2004 in a tertiary health care center.
Results:
Most (72.7%) cases were of fibrous dysplasia and were under 25 years of age (72%). Maxilla was the most common bone involved (81%). Lateral rhinotomy was the main approach for surgical resection. One patient underwent bilateral optic nerve decompression (left side therapeutic and on right side prophylactic). Six (54.5%) cases had recurrences that were managed by either radical surgery (total maxillectomy) or by further shaving off the lesion.
Conclusion:
Treatment of craniofacial fibro-osseous lesions is highly individualized. A conservative approach may not be able to treat all cases of craniofacial fibro-osseous lesions. A more radical approach that includes a craniofacial resection or a total maxillectomy may be warranted in few cases.
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