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Related Experiment Videos

Hypercoagulation testing in ischemic stroke.

Aliyah Rahemtullah1, Elizabeth M Van Cott

  • 1Coagulation Laboratory, Division of Laboratory Medicine, Department of Pathology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA.

Archives of Pathology & Laboratory Medicine
|June 7, 2007
PubMed
Summary
This summary is machine-generated.

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Laboratory tests for hypercoagulability can aid in stroke risk assessment. Certain tests like C-reactive protein and homocysteine are useful for high-risk patients, while others are reserved for specific populations.

Area of Science:

  • Neurology
  • Hematology
  • Clinical Pathology

Background:

  • The role of hypercoagulability testing in stroke management remains unclear.
  • Assessing hypercoagulability is crucial for understanding ischemic stroke risk.

Purpose of the Study:

  • To review existing literature on hypercoagulability tests for ischemic stroke.
  • To provide recommendations for laboratory testing in stroke risk stratification.

Main Methods:

  • Systematic review of published articles on hypercoagulation tests.
  • Emphasis on prospective studies evaluating stroke prediction and cerebral vein thrombosis.

Main Results:

  • C-reactive protein, homocysteine, antiphospholipid antibodies, and lipoprotein(a) show potential utility.

Related Experiment Videos

  • Prospective data supports the use of these markers in high-risk stroke patients.

    • Conclusions:

    • Selected hypercoagulability tests can inform stroke risk assessment.
    • Routine testing of Factor V Leiden and other specific factors is not recommended for all patients.
    • Certain tests are valuable in specific populations, including pediatric stroke and cerebral vein thrombosis.