Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cocaine use and stroke.

Sean D Treadwell1, Tom G Robinson

  • 1Department of Integrated Medicine, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, Leicester, UK. seantreadwell@hotmail.com

Postgraduate Medical Journal
|June 7, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Current status of statin therapy for stroke prevention.

Expert review of cardiovascular therapy·2011
Same author

Measurement of cerebral blood flow responses to the thigh cuff maneuver: a comparison of TCD with a novel MRI method.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism·2010
Same author

Freezing of gait in older people: associated conditions, clinical aspects, assessment and treatment.

Postgraduate medical journal·2010
Same author

Malignant middle cerebral artery (MCA) infarction: pathophysiology, diagnosis and management.

Postgraduate medical journal·2010
Same author

Diseases and impairments as risk factors for onset of disability in the older population in England and Wales: findings from the Medical Research Council Cognitive Function and Ageing Study.

The journals of gerontology. Series A, Biological sciences and medical sciences·2005

Cocaine use is linked to an increased risk of stroke, affecting young adults. This review examines the mechanisms behind cocaine-induced strokes, including vasospasm and vasculitis.

Area of Science:

  • Neurology
  • Cardiovascular Medicine
  • Toxicology

Background:

  • Stroke is a leading cause of death globally.
  • Cocaine use, particularly crack cocaine, has been associated with a rise in stroke incidence.
  • Young adults are increasingly affected by cocaine-induced strokes.

Purpose of the Study:

  • To review the evidence on the mechanisms of cocaine-induced stroke.
  • To explore factors contributing to both ischemic and hemorrhagic stroke in cocaine users.

Main Methods:

  • Literature review of case reports and studies on cocaine and stroke.
  • Analysis of proposed pathophysiological mechanisms.
  • Examination of evidence for vasospasm, vasculitis, platelet aggregation, cardioembolism, and hypertensive surges.

Related Experiment Videos

Main Results:

  • Cocaine is a potent central nervous system stimulant.
  • Mechanisms include vasospasm, cerebral vasculitis, enhanced platelet aggregation, cardioembolism, and hypertensive surges.
  • Altered cerebral autoregulation may play a role.

Conclusions:

  • The exact mechanism of cocaine-induced stroke is multifactorial.
  • Further research is needed to fully elucidate the relationship between cocaine use and stroke.
  • Understanding these mechanisms is crucial for prevention and treatment strategies.