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Related Experiment Video

Updated: May 1, 2026

The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease
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Does this patient have dementia?

Tracey Holsinger1, Janie Deveau, Malaz Boustani

  • 1Department of Psychiatry, Durham VA Medical Center, Durham, NC, USA. tracey.holsinger@va.gov

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|June 7, 2007
PubMed
Summary
This summary is machine-generated.

Brief cognitive screening tests aid dementia diagnosis in primary care. The Memory Impairment Screen and informant reports show promise for detecting cognitive impairment in older adults.

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Area of Science:

  • Gerontology
  • Neurology
  • Primary Care Medicine

Background:

  • Millions in the US experience dementia or memory complaints.
  • Early detection of cognitive impairment is crucial for timely dementia diagnosis.
  • Brief screening tools can assist in primary care settings.

Purpose of the Study:

  • To review the literature on the practicality and accuracy of brief cognitive screening instruments in primary care.
  • To update previous reviews on cognitive screening tools for dementia.

Main Methods:

  • Searched MEDLINE and psycINFO databases (2000-2006).
  • Included studies of patients aged 60+ with dementia diagnosis confirmation.
  • Assessed 29 studies using 25 different screening instruments for eligibility and quality.

Main Results:

  • Evaluated 38 unique instrument/study combinations.
  • Mini-Mental State Examination (MMSE) showed median likelihood ratios (LRs) of 6.3 (positive) and 0.19 (negative).
  • Memory Impairment Screen (4 min) had LRs of 33 (positive) and 0.08 (negative); informant reports had LR of 6.5 for dementia.

Conclusions:

  • Clinicians should choose primary screening tools based on patient population and awareness of demographic scoring effects.
  • Consider adding secondary tools for specific situations.
  • Clock drawing tests can be useful but require appropriate scoring and may miss mild impairment.