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Related Experiment Video

Updated: Jul 14, 2026

Chronic Social Defeat Stress in Early Adolescent Male Mice

Chronic Social Defeat Stress in Early Adolescent Male Mice

Published on: January 24, 2025

Deliberate self-harm in adolescents.

Gwendolyn Portzky¹, Kees van Heeringen

¹Unit for Suicide Research, Department of Psychiatry, University Hospital Gent, Gent, Belgium.

Current Opinion in Psychiatry

|June 7, 2007

Summary

Young people who deliberately harm themselves face increased risks for future mental health issues and suicidal behavior. Research highlights risk factors and effective treatments like cognitive behavior therapy for adolescent self-harm.

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Last Updated: Jul 14, 2026

Chronic Social Defeat Stress in Early Adolescent Male Mice

Chronic Social Defeat Stress in Early Adolescent Male Mice

Published on: January 24, 2025

Area of Science:

Psychiatry
Adolescent Health
Mental Health Research

Background:

Deliberate self-harm in youth is a significant indicator of future mental health challenges.
Increased risk of suicidal behavior is associated with early-onset self-harm.

Purpose of the Study:

To review literature on deliberate self-harm in young people published between March 2005 and December 2006.
To synthesize recent findings on risk factors, predictors, and treatment of adolescent self-harm.

Main Methods:

Literature review of English-language journals.
Analysis of recent follow-up studies on deliberate self-harm in adolescents.

Main Results:

Depressive disorders, poor problem-solving, exposure to suicidal behavior, and family factors are key risk factors.
Selective serotonin reuptake inhibitors (SSRIs) are under continued study for treating self-harm in youth.
Cognitive behavior therapy (CBT) shows positive outcomes for depressed and suicidal youth.

Conclusions:

Adolescent self-harm necessitates further research into neurobiological correlates of suicidality.
The link between antidepressant use and suicidal behavior in young people remains debated.
Preventative measures for youth suicidal behavior require additional investigation.