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Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis
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Screening for problem drinking : Comparison of CAGE and AUDIT.

K A Bradley1, K R Bush, M B McDonell

  • 1Health Services Research and Development, VA Puget Sound Health Care System (Seattle Division), Seattle, WA, USA.

Journal of General Internal Medicine
|June 7, 2007
PubMed
Summary

The Alcohol Use Disorders Identification Test (AUDIT) outperformed the CAGE questionnaire in identifying heavy drinking and alcohol abuse among male outpatients. Self-administered AUDIT is a superior screening tool for problem drinking in this population.

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Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
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Area of Science:

  • Clinical Medicine
  • Psychiatry
  • Public Health

Background:

  • Heavy and problem drinking are significant public health concerns.
  • Effective screening tools are crucial for early detection and intervention in clinical settings.

Purpose of the Study:

  • To compare the self-administered CAGE, Alcohol Use Disorders Identification Test (AUDIT), and an augmented CAGE for detecting heavy and problem drinking.
  • To evaluate the diagnostic accuracy of these questionnaires in a male outpatient population.

Main Methods:

  • Cross-sectional survey conducted in three Department of Veterans Affairs general medical clinics.
  • A random sample of male outpatients (n=261) who consumed at least 5 drinks in the past year participated.
  • Screening questionnaires (CAGE, augmented CAGE, AUDIT) were compared against established diagnostic standards using receiver operating characteristic curves (AUROCs).

Main Results:

  • For detecting active alcohol abuse or dependence, the augmented CAGE showed the highest AUROC (0.871), followed by CAGE (0.820) and AUDIT (0.777).
  • For identifying heavy drinking, the AUDIT performed best (AUROC 0.870).
  • For identifying both heavy drinking and active alcohol abuse/dependence, the AUDIT was superior (AUROC 0.861) to the augmented CAGE.

Conclusions:

  • The self-administered AUDIT is a superior tool for identifying patients with heavy drinking or active alcohol abuse/dependence compared to the CAGE in this male outpatient population.
  • The choice of screening tool may depend on the specific diagnostic goal (heavy drinking vs. abuse/dependence).