Related Experiment Video
Updated: Jul 14, 2026

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Closed funnel-shaped proliferative vitreoretinopathy in patients with cognitive disabilities
Takayuki Baba1, Sumiyoshi Tanaka, Akira Maesawa
1Department of Ophthalmology, Mitsui Memorial Hospital, Japan.
Background And Objective:
To report severe proliferative vitreoretinopathy (PVR) cases in patients with cognitive disabilities treated with vitrectomy.
Patients And Methods:
This retrospective study included 10 eyes of 9 consecutively enrolled patients with cognitive disabilities. The severity of PVR was grade C type 2345 with widespread preretinal and subretinal proliferation in all cases. The surgical management was vitrectomy with scleral buckling, retinotomy, removal of preretinal and subretinal proliferation, and silicone oil tamponade. Mandatory prone positioning and limb restraint were not indicated. Postoperative anatomic and functional success were studied. The follow-up ranged from 3 to 62 months (mean: 25.8 months).
Results:
The retina was attached in 10 eyes (100%) at the final examination. Functional success, based on an improvement in patient daily activity, was achieved in 4 patients (44%). No severe complications were noted.
Conclusions:
Treatment with vitrectomy was effective to manage severe PVR in patients with cognitive disabilities and contributed to improve daily life.
Related Concept Videos
Diabetic Retinopathy
Photoreceptors and Visual Pathways
Glaucoma: Overview
