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Published on: September 26, 2018
[Guideline 'Cardiovascular Risk Management']
J S Burgers1, M L Simoons, A W Hoes
1Kwaliteitsinstituut voor de Gezondheidszorg CBO, Postbus 20.064, 3502 LB Utrecht. j.burgers@cbo.nl
Insights
This guideline provides an integrated approach to managing cardiovascular disease (CVD) risk factors. It outlines risk assessment and treatment strategies, including lifestyle counseling and pharmacotherapy, for high-risk individuals to prevent future cardiovascular events.
Area of Science:
- Cardiology
- Preventive Medicine
- Public Health
Context:
- Atherothrombosis significantly contributes to cardiovascular disease (CVD) burden.
- Effective management of modifiable risk factors is crucial for CVD prevention.
- Clinical guidelines are essential for standardizing evidence-based cardiovascular risk management.
Purpose:
- To provide an integral approach to managing all relevant risk factors for CVD caused by atherothrombosis.
- To establish criteria for assessing CVD risk factors in various patient populations.
- To guide therapeutic interventions, including lifestyle counseling and pharmacotherapy, for high-risk individuals.
Summary:
- The guideline targets patients with existing CVD, diabetes mellitus type 2 (DM2), hypertension, hypercholesterolemia, and specific demographic groups (e.g., older smokers).
- Assessment of CVD risk factors is recommended for eligible individuals, with lifestyle counseling for all high-risk patients.
- Pharmacological recommendations include acetylsalicylic acid, beta-blockers, ACE inhibitors, and statins based on specific criteria (e.g., LDL-cholesterol levels).
- For patients with DM2, statins, blood pressure-lowering drugs, and glucose-lowering drugs are recommended under specific conditions.
- In patients without CVD and DM2, treatment is initiated if the estimated 10-year CVD mortality risk exceeds 10%.
Impact:
- Facilitates personalized treatment and follow-up plans based on individual risk profiles, comorbidities, and patient preferences.
- Aims to reduce the incidence and mortality associated with cardiovascular diseases.
- Promotes a proactive and comprehensive strategy for cardiovascular risk management in clinical practice.
Abstract:
The aim of the clinical practice guideline 'Cardiovascular risk management' is an integral approach to all relevant risk factors for cardiovascular disease (CVD) caused by atherothrombosis. Patients with CVD, diabetes mellitus type 2 (DM2), elevated blood pressure or cholesterol, men of 50 years or older who smoke and women of 55 years or older who smoke are eligible for assessment of relevant risk factors for CVD. All high-risk patients should receive lifestyle counselling. In patients with CVD the use of acetylsalicylic acid and often, depending on the specific disease, a beta-blocker or an angiotensin converting enzyme (ACE) inhibitor are recommended. The use of a statin is recommended if the LDL-cholesterol concentration is > or = 2.5 mmol/l. In patients with DM2, the use of statins is recommended if LDL-cholesterol is > or = 2.5 mmol/l and use of a blood pressure lowering drug with a systolic blood pressure > or = 140 mmHg, as well as glucose lowering drugs. In patients without CVD and DM2, the need for drug treatment will be determined by estimation of the absolute 10-year mortality risk of CVD. Treatment is recommended if this risk exceeds 10%. The treatment and follow-up plan will be determined individually, depending on the risk profile, morbidity, comorbidity and patient's preferences.
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