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Epithelioid hemangioendothelioma of the liver
Shahzad Ashraf1, H M Ashraf, Nadira Mamoon
1Department of Medicine, Combined Military Hospital, Malir Cantt, and Department of Pathology, Foundation University Medical College, Rawalpindi. shahzad-ashraf@yahoo.com
Epithelioid hemangioendothelioma is an intermediate grade malignant neoplasm of vascular origin. The tumor involves the liver and lungs, but other organs are affected too. The key to the diagnosis is identification of cells of endothelial origin containing Factor VIII R antigen. Surgical resection of isolated lesions is the treatment of choice; with unpredictable results reported for chemotherapy, radiotherapy, and resection of multiple lesions. The prognosis is very variable, and ranges from few months to more than 25 years.
Epithelioid hemangioendothelioma is an intermediate grade malignant neoplasm of vascular origin. The tumor involves the liver and lungs, but other organs are affected too. The key to the diagnosis is identification of cells of endothelial origin containing Factor VIII R antigen. Surgical resection of isolated lesions is the treatment of choice; with unpredictable results reported for chemotherapy, radiotherapy, and resection of multiple lesions. The prognosis is very variable, and ranges from few months to more than 25 years.
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