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Prospective analysis on the relation between pain and prostate volume during transrectal prostate biopsy
Tae Jin Yun1, Hak Jong Lee, Seung Hyup Kim
1Seoul National University College of Medicine, Seoul National University Bundang Hospital, Institute of Radiation Medicine, Seoul National University Medical Research Center, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea.
Patients with larger prostates experience more pain during and after transrectal ultrasound (TRUS) guided biopsy. This suggests a need for enhanced pain management strategies for these individuals undergoing the procedure.
Area of Science:
- Urology
- Pain Management
- Medical Imaging
Background:
- Transrectal ultrasound (TRUS) guided prostate biopsy is a common procedure for diagnosing prostate cancer.
- Pain perception during and after TRUS biopsy can vary among patients.
- Prostate volume is a potential factor influencing pain during TRUS biopsy.
Purpose of the Study:
- To investigate the association between prostate volume and pain experienced during TRUS guided biopsy.
- To compare pain scores in patients with larger versus smaller prostate volumes.
Main Methods:
- 71 patients undergoing TRUS biopsy were included.
- Periprostatic neurovascular bundle block with lidocaine was administered prior to biopsy.
- Pain was assessed using a Visual Analogue Scale (VAS) at three time points: during block, during biopsy, and 20 minutes post-biopsy.
- Patients were categorized into large (>40 cc) and small (<=40 cc) prostate volume groups for analysis.
Main Results:
- The mean prostate volume was 42.2 cc.
- Patients with larger prostates reported significantly higher pain scores during (VAS 2) and after (VAS 3) the biopsy compared to those with smaller prostates (p < 0.05).
- No significant difference in pain scores was observed during the lidocaine block (VAS 1) between the groups.
Conclusions:
- Larger prostate volume is associated with increased pain during and after TRUS guided prostate biopsy.
- Consideration of additional analgesic strategies may be beneficial for patients with larger prostates undergoing TRUS biopsy.
- Further research into tailored pain management for TRUS biopsy based on prostate size is warranted.
