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The Synthesis, Characterization and Reactivity of a Series of Ruthenium N-triphosPh Complexes
Published on: April 10, 2015
Hydrolytic cleavage of DNA by a ruthenium(II) polypyridyl complex
Megha S Deshpande1, Anupa A Kumbhar, Avinash S Kumbhar
1Department of Chemistry, University of Pune, Pune- 411 007, India.
Inorganic Chemistry
|June 9, 2007
Abstract:
The complex [Ru(bpy)2(BPG)]Cl2 (1) containing hydrogen-bond donor (N-H atoms) and acceptor (O atoms) groups mediates hydrolytic cleavage of plasmid pBR322 DNA in an enzyme-like manner. The kinetic aspects of DNA cleavage under pseudo- and true-Michaelis-Menten conditions are detailed.
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