Effects of individual components of multiple behavior changes: the PREMIER trial
Eva Obarzanek1, William M Vollmer, Pao-Hwa Lin
1National Heart, Lung, and Blood Institute, Bethesda, MD 20892-7936, USA. obarzane@nhlbi.nih.gov
Objectives:
To assess contributions of individual lifestyle changes on systolic blood pressure (SBP) changes.
Methods:
We examined associations between lifestyle behavior changes and SBP after 6 and 18 months in 782 PREMIER trial participants.
Results:
In multivariate models omitting weight, predicted SBP reductions ranged from (1)/2 to 1(1)/2 mm Hg for reduced urinary sodium, improved fitness, and adherence to the DASH diet (except sodium at 18 months). With weight included, only fitness change additionally predicted SBP at 18 months.
Conclusions:
Several lifestyle behavior changes are important for BP lowering, but are difficult to detect when weight is included in multivariate models.
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