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Time-series analysis of meningococcal disease in Catalonia

Angela Domínguez1, Pilar Muñoz, Neus Cardeñosa

  • 1Epidemiological Surveillance Service, Department of Health, Generalitat of Catalonia, Barcelona, Spain. angela.dominguez@gencat.net

Annals of Epidemiology
|June 9, 2007
PubMed
Abstract

Insights

Meningococcal disease serogroups B and C in Catalonia showed different temporal patterns. Serogroup B cases correlated with influenza epidemics, while serogroup C cases linked to influenza and inversely to vaccination campaigns.

Area of Science:

  • Epidemiology
  • Infectious Disease Dynamics
  • Public Health Surveillance

Background:

  • Meningococcal disease incidence in Catalonia was elevated in 1996-1997.
  • Analysis of temporal trends for serogroup B and C meningococcal disease is crucial for public health interventions.

Purpose of the Study:

  • To analyze the temporal behavior of serogroup B and C meningococcal disease cases in Catalonia.
  • To understand the epidemiological patterns of different meningococcal serogroups over time.

Main Methods:

  • Time series analysis of confirmed meningococcal disease cases from 1996 to 2004.
  • Application of Poisson regression models (GLM and ZIP) to analyze serogroup B and C case data respectively.

Main Results:

  • Temporal evolution of serogroup B and C meningococcal disease cases were correlated.
  • Serogroup B cases showed association with influenza epidemics.
  • Serogroup C cases exhibited association with influenza epidemics and inverse association with vaccination campaigns.

Conclusions:

  • Serogroup B and C meningococcal disease exhibit distinct temporal dynamics.
  • Understanding these distinct patterns can inform and evaluate vaccination strategies for meningococcal disease.

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