Related Experiment Video
Updated: Jul 12, 2026

Oscillation and Reaction Board Techniques for Estimating Inertial Properties of a Below-knee Prosthesis
Published on: May 8, 2014
The work of the CONRAD task group 5.2: research studies on biokinetic models
D Nosske1, V Berkovski, A Birchall
1Federal Office for Radiation Protection, Department of Radiation Protection and Health, 85762 Oberschleissheim, Germany. dnosske@bfs.de
Abstract:
The objective of this Task Group is the coordination of research studies on biokinetic models and the evaluation of the implications of new biokinetic models on dose assessment and safety standards. For this the new ICRP models, which will be used for a revision of ICRP Publications 30, 54, 68 and 78, are implemented into six different computer codes in five European countries and quality assured by intercomparison procedures. The work has started with the implementation of the new ICRP Alimentary Tract Model. New systemic models and the new NCRP wound model will follow. The work also includes the evaluation of experimental results in terms of formulation by the new model structures and a quality assurance of model formulation.
Related Concept Videos
Pharmacokinetic Models: Overview
There are three primary types of models: empirical, compartment, and physiological. Empirical models, with minimal assumptions,...
Clearance Models: Physiological Models
The organ's clearance rate depends on the blood flow to the organ and the extraction ratio (E). The extraction ratio describes the organ's proficiency in drug...
Mechanistic Models: Compartment Models in Individual and Population Analysis
Model Approaches for Pharmacokinetic Data: Physiological Models
Physiological Pharmacokinetic Models: Blood Flow-Limited Versus Diffusion-Limited Models
Pharmacokinetic Models: Comparison and Selection Criterion
Physiological models take a detailed approach by considering specific molecular processes. They can predict drug distribution, metabolism, and elimination changes, providing a comprehensive understanding of how drugs interact with the body.

