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Updated: Jul 14, 2026

3D Modeling of Dendritic Spines with Synaptic Plasticity
Published on: May 18, 2020
Modelling the geometric features and investigating electrical properties of dendrites in a fish thalamic neuron
Wojciech Krzyzanski1, Jonathan Bell
1Department of Pharamaceutical Sciences, University of Buffalo, State University of New York, Buffalo, NY 14260, USA. wk@buffalo.edu
Abstract:
A certain pacific fish has a thalamic nerve cell with a unique dendritic geometry. Instead of the cell having a branching dendritic structure, the large cell of the corpus glomerulosum has, generally, a single dendritic stalk with a large bulbous tip. We formulate a cable-theory model that incorporates the geometry, and then, we solve the problem for a single, localized synaptic current source at the bulb. From the solution representation, we numerically examine the characteristics of the postsynaptic potential due to the presence of the bulbous tip.
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