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Updated: Jul 14, 2026

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
Minimally invasive management of intrathoracic leaks after esophagogastrectomy
Ninh T Nguyen1, Marcelo W Hinojosa, Christine Fayad
1Department of Surgery, University of California, Irvine, Medical Center, Orange, California 92868, USA. ninhn@uci.edu
Abstract:
Enthusiasm for minimally invasive esophagectomy is increasing. When feasible, the laparoscopic and thoracoscopic Ivor Lewis esophagogastrectomy with construction of an intrathoracic anastomosis is favored. A potential catastrophic consequence of an intrathoracic anastomosis is a postoperative leak. In this review, the authors summarize the current understanding of the pathophysiology and the management of intrathoracic leak using minimally invasive surgical techniques.
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