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Published on: January 7, 2019
Contemporary outcomes in bladder exstrophy
Patricio C Gargollo1, Joseph G Borer
1Department of Urology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA.
Insights
Bladder exstrophy care has evolved, with recent focus on long-term outcomes like psychosexual development and social adaptation alongside traditional measures. Further high-quality research is needed for definitive clinical insights.
Area of Science:
- Pediatric Urology
- Developmental Biology
- Surgical Outcomes
Background:
- Bladder exstrophy poses significant surgical and clinical challenges.
- Historically, management focused on surgical techniques.
- Recent literature increasingly addresses long-term patient outcomes.
Purpose of the Study:
- To review recent advancements in bladder exstrophy patient care.
- To examine contemporary medical and psychosocial outcomes in this population.
Main Methods:
- Literature review of recent developments in bladder exstrophy management.
- Analysis of publications focusing on long-term patient outcomes.
Main Results:
- Shift in focus from surgical techniques to comprehensive long-term outcomes.
- Increased attention to psychosexual development, sexual function, and social adaptation.
- Outcomes now considered alongside urinary continence and renal function.
Conclusions:
- No well-designed prospective trials currently exist for bladder exstrophy clinical outcomes.
- Current understanding relies heavily on retrospective data with potential biases.
- Need for robust prospective studies to improve clinical management and outcomes.
Purpose Of Review:
The patient with bladder exstrophy presents complex surgical and clinical management challenges to the pediatric urologist. This review aims to present recent developments in the care of these patients as well as to review contemporary medical outcomes.
Recent Findings:
Most of the early literature pertaining to bladder exstrophy has focused on surgical techniques and management. In the last 10-20 years, however, there has been an increase in the number of publications dealing with long-term outcomes in these patients. Psychosexual development, sexual function and social adaptation have received as much attention as urinary continence status, bladder, and renal function. This review will examine these topics.
Summary:
Despite the complex nature of bladder exstrophy, there are no well designed, prospective trials examining clinical outcomes in these patients. Until better trials are planned, executed and published, much of what we know about patients with bladder exstrophy will be based on retrospective observations with significant biases.
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