Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Paraneoplastic effects on neurophthalmologic function.

Debamalya Ray1, Ajay Nigam

  • 1Department of Otorhinolaryngology (ENT), Blackpool Victoria Hospital, Blackpool, England, U.K. debamalyaray@hotmail.com

Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [And] European Academy of Otology and Neurotology
|June 15, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Primary thyroid squamous cell carcinoma presenting as a left-sided neck lump.

BMJ case reports·2021
Same author

A rare case of acquired benign tracheoesophageal fistula.

Journal of surgical case reports·2020
Same author

Severe psychosis due to Cushing's syndrome in a patient with a carcinoid tumour in the lung: a case report and review of the current management.

World journal of surgical oncology·2015
Same author

Idiopathic bilateral auricular petrification.

Ear, nose, & throat journal·2012
Same author

Double-blind randomised controlled trial comparing Merocel with Rapid Rhino nasal packs after routine nasal surgery.

Rhinology·2004

Paraneoplastic syndromes can present with rare otoneurophthalmologic symptoms before cancer diagnosis. Early investigation of these symptoms is crucial for timely cancer detection and treatment.

Area of Science:

  • Neurology
  • Oncology
  • Ophthalmology

Background:

  • Paraneoplastic neurologic syndromes (PNS) are rare, especially when presenting before cancer identification.
  • Otoneurophthalmologic manifestations are uncommon PNS symptoms.

Observation:

  • A rare case of combined paraneoplastic brainstem/limbic encephalitis and Lambert-Eaton myasthenic syndrome is presented.
  • The patient had small cell lung cancer, positive antiamphiphysin antibodies, and initial otoneurophthalmologic symptoms.

Findings:

  • This combined PNS presentation with positive antiamphiphysin antibodies (but negative anti-Hu antibodies) is exceptionally rare.
  • Clinical and laboratory tests confirmed the diagnosis.

Implications:

Related Experiment Videos

  • Prompt investigation of unexplained otoneurophthalmologic symptoms is vital for early cancer detection.
  • Early diagnosis improves cancer treatment outcomes and patient prognosis.