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[Sensitization against storage mites in allergic rhinopathy]
1Klinik und Poliklinik für Hals-Nasen-Ohrenkranke, Ludwig-Maximilians-Universität München.
Laryngo- Rhino- Otologie
|December 1, 1991
Summary
Storage mites are increasingly linked to allergic airway diseases, particularly in rural populations. Our study found significant sensitization rates to common storage mites, suggesting their importance in allergic rhinitis.
Area of Science:
- Allergen immunotherapy
- Environmental allergies
- Immunological assays
Context:
- Storage mites are emerging as significant allergens contributing to allergic airway diseases.
- Sensitization to storage mites is frequently observed in agricultural workers and those in rural environments.
- Previous research has primarily focused on European populations, with limited data on specific regional prevalences.
Purpose:
- To investigate the prevalence of sensitization to storage mites in a Bavarian rural population with known house dust mite allergy.
- To determine the specific IgE antibody levels against common storage mite species.
- To assess the clinical relevance of storage mites as allergens in allergic rhinitis.
Summary:
- This study analyzed sera from patients with diagnosed house dust mite allergy (RAST class 2-4 for Dermatophagoides pteronyssinus).
- Specific IgE antibodies against storage mites were measured using the Melja EAST-technique.
- Sensitization rates were found to be 7% for Acarus siro (d70), 17% for Lepidoglyphus destructor (d71), 3% for Tyrophagus putrescentiae (d72), and 13% for Glycyphagus domesticus (d73).
Impact:
- Storage mites represent relevant allergens in allergic rhinitis, especially within rural Bavarian communities.
- The findings support the routine testing for storage mite allergies in patients presenting with perennial allergic rhinitis.
- This research highlights the need to consider storage mites in the differential diagnosis of allergic respiratory conditions.