Preliminary analysis of the G178A polymorphism of insulin-like factor 3 in male infertility

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Yeo-Jin Yun1, Han-Chul Lee, Jee-Eun Kim

  • 1Functional Genomics Lab, CHA Research Institute, Bundang Campus, College of Medicine, Pochon CHA University, Sungnam City, Kyunggi-Do, Korea.

Fertility and Sterility
|June 15, 2007
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Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...