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Increasing prevalence of gastroschisis repairs in the United States: 1996-2003
Sonia M Alvarez1, Randall S Burd
1Division of Pediatric Surgery, Department of Surgery, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA.
Insights
The rate of gastroschisis repairs in the United States doubled between 1996 and 2003. This study analyzed national data to confirm increasing gastroschisis repair trends nationwide.
Area of Science:
- Pediatric Surgery
- Public Health Surveillance
Background:
- Gastroschisis prevalence has been increasing nationally and internationally.
- Understanding trends in gastroschisis repair is crucial for public health planning.
Purpose of the Study:
- To identify national trends in gastroschisis repair rates using a representative database.
- To analyze changes in gastroschisis repair prevalence from 1996 to 2003.
Main Methods:
- Utilized the Nationwide Inpatient Sample (NIS) database from 1996-2003.
- Incorporated birth data from the National Center for Health Statistics.
- Employed survey statistics to account for NIS sampling design.
Main Results:
- A total of 9,459 gastroschisis repairs were performed between 1996 and 2003.
- A significant nationwide increase in gastroschisis repair rates was observed.
- The procedure rate doubled from 1996 to 2003 (rate ratio, 2.0).
- No significant change in unadjusted hospital mortality was noted.
Conclusions:
- Gastroschisis repair rates significantly increased nationwide and regionally.
- These findings align with previously reported local and state-level trends.
Purpose:
Local and state registries have shown recent increases in the prevalence of gastroschisis in the United States and abroad. The purpose of this study was to use a nationally representative database to identify national trends in the prevalence of gastroschisis repairs.
Methods:
Records of infants undergoing gastroschisis repair were identified in the Nationwide Inpatient Sample from 1996 to 2003. Birth data were obtained from the National Center for Health Statistics and used to calculate the rate of procedures/live births stratified by US census region. Survey statistics were used to account for the sampling design of the Nationwide Inpatient Sample database.
Results:
Between 1996 and 2003, a total of 9459 gastroschisis repairs were performed in the United States (3 procedures for every 10,000 births). A significant increase in the population-based rate of these procedures was observed in each census regions and nationwide. A twofold higher procedure rate was observed in 2003 than in 1996 (rate ratio, 2.0; 95% confidence interval, 1.1-2.9; P < .001). No significant change in unadjusted hospital mortality was observed regionally or nationally.
Conclusions:
The population-based rate of gastroschisis repairs significantly increased regionally and nationwide between 1996 and 2003, paralleling recent trends described at the local and state level.
