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Updated: Jul 14, 2026

Isolation of Human Endometrial Stromal Cells for In Vitro Decidualization
Published on: September 1, 2018
Decidual cast in a girl receiving depot medroxyprogesterone acetate--a case report
Vivekanand Singh1, Nasreen Talib, Julie Strickland
1Departments of Pathology, Pediatrics, and Gynecological Surgery, Children's Mercy Hospital, Kansas City, Missouri 64108, USA. vsingh@cmh.edu
Background:
The passage of tissue per vaginam in a young girl raises several diagnostic considerations that include aborted pregnancy, benign polyp, rhabdomyosarcoma, and rarely decidual cast.
Case:
A 9-yr-old girl who was receiving depot medroxy-progesterone acetate to suppress menstruation passed tissue per vaginam. Pathological examination of the tissue showed a decidual cast with no chorionic villi, while a serum hCG test was also negative.
Conclusions:
Decidual cast formation is a rare side effect of progestogen use and should be considered in the differential diagnosis of passage of tissue per vaginam.
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