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Related Experiment Video

Updated: Jul 14, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

Totally normothermic aortic arch replacement without circulatory arrest.

Gilles D Touati1, Paul Marticho, Moataz Farag

  • 1Department of Cardiovascular Surgery, Centre Hospitalier et Universitaire d'Amiens, Hôpital Sud, 80054 Amiens Cedex 01, France. gtouati.hms@invivo.edu

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|June 15, 2007
PubMed
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This study presents a novel normothermic aortic arch replacement technique, avoiding profound hypothermic circulatory arrest complications. The method ensures physiological cerebral blood flow and body perfusion, demonstrating safety and efficacy in complex aortic disease surgery.

Area of Science:

  • Cardiovascular Surgery
  • Thoracic Surgery
  • Vascular Surgery

Background:

  • Complex aortic disease necessitates cerebral protection strategies during surgery.
  • Traditional methods using profound hypothermic circulatory arrest have limitations and complications.
  • A revisited strategy employing normothermic aortic arch replacement is proposed.

Purpose of the Study:

  • To evaluate a novel, totally normothermic, complete aortic arch replacement technique.
  • To assess the safety and efficacy of this approach in patients with aortic arch aneurysms and dissections.
  • To compare outcomes with traditional hypothermic methods.

Main Methods:

  • A three-pump system was utilized for normothermic procedures.
  • Antegrade cerebral perfusion was maintained at 70 mmHg (right radial artery).

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Last Updated: Jul 14, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
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Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
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Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

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  • Body perfusion was set at 55 mmHg (left femoral artery), with intermittent myocardial perfusion.

    • Main Results:

    • Two operative in-hospital mortalities (6.8%) were observed.
    • The majority of patients were rapidly extubated with no neurological sequelae.
    • Postoperative courses were uneventful, without coagulopathy or hepato-renal impairment.

    Conclusions:

    • Normothermic aortic arch replacement is a feasible and safe procedure.
    • This technique allows for physiological autoregulation of cerebral blood flow.
    • It effectively maintains body perfusion without elevated vascular resistances.