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Cognitive deficits during status epilepticus and time course of recovery: a case report
Wim Van Paesschen1, Kathleen Porke, Katrien Fannes
1Department of Neurology, University Hospital Gasthuisberg, Katholieke Universiteit Leuven, Belgium. Wim.vanpaesschen@z.kuleuven.ac.be
Abstract:
We describe a young woman with progressive cognitive and neurological deficits during a parietal lobe status epilepticus (SE). Ictal FDG-PET showed left parietal lobe hypermetabolism and frontal lobe hypometabolism with concomitant EEG slowing. Cognitive and neurological deficits fully reversed more than 1 year after seizure remission, and were associated with normalization of FDG-PET and EEG. Our findings suggest that ictal hypometabolism and EEG delta activity at a distance from the epileptic focus were seizure-related phenomena, possibly representing inhibition in seizure propagation pathways, which could be responsible for the epileptic encephalopathy.
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