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Updated: Jul 14, 2026

Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
Published on: December 23, 2022
Percutaneous left ventricular assist device complicated by a patent foramen ovale: importance of identification and
Pranav Loyalka1, Gary M Idelchik, Biswajit Kar
1Department of Heart Transplantation and Mechanical Support, Division of Cardiology, St. Luke's Episcopal Hospital and Texas Heart Institute, Houston, Texas 77030, USA. pranavloyalka@yahoo.com
Abstract:
Recently, the TandemHeart percutaneous left ventricular assist device (pVAD) has become available as a means to both resuscitate and support patients in cardiogenic shock pending myocardial recovery or definitive surgical or percutaneous intervention. Hypoxia during pVAD support may arise from multiple pulmonary etiologies, including pulmonary edema and mechanisms resulting in right-to-left shunting. We report two cases of patients supported by pVADs in who patent foramen ovale (PFO) present as right-to-left shunts following initiation of TandemHeart support. A review of the mechanisms and hemodynamics resulting in PFO patency during pVAD support as well as suggestions for management are presented.
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