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Published on: May 3, 2018
Estimation of central pressure augmentation using automated radial artery tonometry
Vojtech Melenovsky1, Barry A Borlaug, Barry Fetics
1Department of Cardiology, IKEM, Prague, Czech Republic.
Automated radial analysis of augmentation index (AI) offers a practical alternative to carotid tonometry for assessing central blood pressure augmentation. This method shows promise for clinical trials and individual cardiac risk stratification.
Area of Science:
- Cardiovascular Physiology
- Biomedical Engineering
- Clinical Diagnostics
Background:
- Peripheral wave reflection increases central blood pressure, impacting cardiac load.
- Augmentation index (AI) quantifies this pressure augmentation but is difficult to measure from the carotid artery.
- Carotid tonometry is challenging to standardize, necessitating alternative methods.
Purpose of the Study:
- To evaluate automated radial pressure analysis as a viable alternative to carotid tonometry for measuring AI.
- To assess the correlation between radial AI (rAI) and carotid AI (cAI).
- To determine if rAI can accurately predict cardiac load based on AI thresholds.
Main Methods:
- Measured carotid AI (cAI) and radial AI (rAI) in 46 volunteers.
- Assessed AI at rest, during a cold-pressor test, and after nitroglycerin administration.
- Correlated cAI and rAI with each other and with cardiac load indices.
Main Results:
- cAI and rAI showed strong correlation (r=0.81) independent of demographic and hemodynamic factors.
- Changes in rAI and cAI during provocative maneuvers also correlated significantly (r=0.77).
- rAI accurately predicted the threshold where increased AI is associated with greater cardiac load (88% accuracy).
Conclusions:
- Automated radial AI analysis is a simple and effective method for assessing central pressure augmentation.
- rAI shows consistency in population studies and is suitable for clinical trials.
- rAI can help stratify individual cardiac risk by predicting increased left ventricular loading.
Related Concept Videos
Assessment of blood pressure in brachial artery(two-step method)
Sites for measuring blood pressure
The Brachial Artery: Primary Site for Blood Pressure Measurement
Equipments Used To Measure Blood Pressure
This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
Assessment of blood pressure in brachial artery(one-step method)
Prepare for the Procedure:
Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Assessment of radial pulse
The radial pulse, located at the wrist, is often the preferred site for assessing peripheral pulse because of its accessibility and dependability. The process of determining the radial pulse involves several steps:
