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Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
[About combined forms of dysentery and salmonellosis]
Abstract:
In Moscow, acute infectious diseases constitute more than 30% of all infectious pathology of adult population. Such combined forms as a combination of shigellosis and salmonellosis exist along with monoinfections. Addition of salmonellosis to dysentery does not necessarily worsen the course of the latter and in some cases does not express itself clinically. However, more often salmonellosis deteriorates the condition of a patient with dysentery: his/her general condition worsens, fever recommences, and defecation becomes more frequent during the recovery period. One of the characteristic forms of salmonellosis is nosoparasitism, the spread of which is not limited to infectious diseases. Nosoparasitism does not present a complication of one infection by another, but is a co-existence of two diseases, one of which as though prepares the organism for the development of the other. Combinations of different infectious diseases (syntropy) require further studies. The author adduces two own observations of the development of salmonella nosoparasitism in patients with shigellosis. The mixed infection had a moderate form.
Insights
Combined bacterial infections like shigellosis and salmonellosis are common. Salmonellosis can worsen shigellosis, leading to prolonged illness and fever, highlighting the need for further research into syntropy.
Area of Science:
- Infectious Diseases
- Microbiology
- Epidemiology
Background:
- Acute infectious diseases represent over 30% of adult pathology in Moscow.
- Combined infections, such as shigellosis and salmonellosis, occur alongside monoinfections.
Observation:
- Salmonellosis addition to shigellosis can range from clinically unapparent to a significant worsening of the patient's condition.
- Nosoparasitism, a form of salmonellosis, can occur with other infectious diseases, not as a complication but as a co-existence.
- The study presents two case observations of Salmonella nosoparasitism in patients with shigellosis.
Findings:
- Mixed infections of shigellosis and salmonellosis were observed to be of moderate severity.
- Salmonellosis often exacerbates shigellosis, causing worsened general condition, recurrent fever, and increased defecation frequency during recovery.
Implications:
- Further research into syntropy, the co-existence of different infectious diseases, is warranted.
- Understanding combined infections is crucial for effective clinical management and public health strategies.
- The findings emphasize the complex interactions between different pathogens within a host.
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