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Updated: Jul 14, 2026

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes
11:42

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes

Published on: November 1, 2012

Crystallization of a Mos1 transposase-inverted-repeat DNA complex: biochemical and preliminary crystallographic

Julia M Richardson1, David J Finnegan, Malcolm D Walkinshaw

  • 1School of Biological Sciences, University of Edinburgh, The King's Buildings, Mayfield Road, Edinburgh EH9 3JR, Scotland. jrichard@staffmail.ed.ac.uk

Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
|June 15, 2007
PubMed

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Transposons make up a significant part of genomes of various organisms. Therefore, it is believed that transposition played a major evolutionary role in speciation by changing genome sizes and modifying gene expression patterns. For example, in bacteria, transposition can lead to conferring antibiotic resistance. Movement of transposable elements within the genetic pool of pathogenic bacteria can aid in transfer of antibiotic-resistant genetic elements. In eukaryotes, transposons can carry out...
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