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Transient renal insufficiency in the neonate related to hyperuricemia and hyperuricosuria
R P Gottlieb1, S Roeloffs, G Galler-Rimm
1Department of Pediatrics, Jefferson Medical College, Philadelphia, Pa.
Abstract:
Transient renal insufficiency in the neonate is frequently the result of hypoperfusion of the kidneys due to circulatory compromise and is associated with a normal renal ultrasound scan. We describe an infant with transient renal insufficiency associated with hyperuricemia, hyperuricosuria and increased echogenicity of the renal medullary pyramids. Transient uric acid nephropathy may be a more common occurrence in the neonate than previously recognized.