Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rare Intraoperative Presentation of a Coexistent Uterine Cystic Mass and Bilateral Ovarian Cystic Masses.

Cureus·2026
Same author

An ensemble machine learning classifier for Parkinson's disease diagnosis using optical coherence tomography angiography.

Scientific reports·2026
Same author

Challenging the Mutation-Only Paradigm: Evidence from Ramsar High Background Radiation Areas.

Journal of biomedical physics & engineering·2025
Same author

A computer-aided diagnosis (CAD) system based on convolutional neural networks for lung cancer diagnosis from 2D [<sup>18</sup>F]- PET/CT images.

Journal of applied clinical medical physics·2025
Same author

Non-Biological Sentient Beings and the Equal Right to Exist.

Journal of biomedical physics & engineering·2025
Same author

Advances and Challenges in Minimally Invasive Myomectomy: A Narrative Review.

Journal of clinical medicine·2025

Related Experiment Videos

Central corneal thickness as a risk factor for glaucoma.

Alireza Mehdizadeh1, Amin Hoseinzadeh, Afsoon Fazelzadeh

  • 1Medical Physics Research Center, Shiraz University of Medical Sciences, Iran.

Medical Hypotheses
|June 15, 2007
PubMed
Summary

Central corneal thickness is a key indicator for glaucoma risk. Thinner corneas are linked to increased stress and potential underestimation of intraocular pressure, raising glaucoma susceptibility.

Related Experiment Videos

Area of Science:

  • Ophthalmology
  • Biomedical Engineering

Background:

  • Glaucoma is a leading cause of worldwide blindness.
  • Several risk factors contribute to glaucoma, including age, race, sex, and intraocular pressure.
  • Central corneal thickness (CCT) is increasingly recognized for its role in glaucoma risk stratification.

Purpose of the Study:

  • To investigate the relationship between central corneal thickness and glaucoma progression.
  • To hypothesize how CCT influences glaucoma susceptibility through stress and intraocular pressure measurement.

Main Methods:

  • The study proposes a hypothesis based on established physiological principles and tonometry.
  • Analysis of the correlation between central corneal thickness, scleral thickness, and stress.
  • Examination of how CCT variations affect intraocular pressure (IOP) measurements.

Main Results:

  • A negative correlation exists between central corneal thickness and ocular stress.
  • Decreased CCT leads to increased neural tissue strain, elevating glaucoma risk.
  • Variations in CCT can cause misestimation of IOP, potentially leading to underdiagnosis and undertreatment.

Conclusions:

  • Central corneal thickness is a significant predictor of glaucoma progression.
  • Incorporating CCT measurement into routine clinical examinations can improve glaucoma screening.
  • This hypothesis elucidates the link between thinner corneas and increased glaucoma susceptibility.