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Updated: Jul 14, 2026

Mucin Agarose Gel Electrophoresis: Western Blotting for High-molecular-weight Glycoproteins
Published on: June 14, 2016
Mucin (qniumucin), a glycoprotein from jellyfish, and determination of its main chain structure
Akiko Masuda1, Takayuki Baba, Naoshi Dohmae
1Riken (The Institute of Physical and Chemical Research), 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Abstract:
We extracted a novel glycoprotein, a member of the mucin family, from five species of jellyfish with high yields (1%-3% dry weight, 0.02%-0.1% wet weight) and determined its main chain structure and molecular mass. The glycoprotein contains unique tandem repeats of eight amino acids, of which two threonine residues are probably glycosylated by N-acetyl-d-galactosamine (GalNAc). We named this substance, which is common in jellyfish and similar to the human mucin MUC5AC, "qniumucin" and suggested the utilization of this compound as a new marine resource.
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