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Treatment selection in primary breast cancer. Pathologic considerations.

H S Gallager

    AJR. American Journal of Roentgenology
    |January 1, 1976
    PubMed
    Summary
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    Cancer·1988
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    Adenoid cystic carcinoma of the breast.

    Human pathology·1987
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    Proton NMR of human breast tumors: correlation with clinical prognostic parameters.

    Journal of surgical oncology·1987

    Minimal breast cancer, including early-stage carcinomas, shows high survival rates with surgical treatment. These small tumors have a low risk of lymph node involvement, ensuring excellent long-term patient outcomes.

    Area of Science:

    • Oncology
    • Surgical Pathology

    Background:

    • Minimal breast cancer encompasses various early-stage lesions, including lobular carcinoma in situ and noninvasive intraductal carcinoma.
    • Defined by a mass ≤ 0.5 cm, these lesions represent a critical stage in breast cancer development.

    Purpose of the Study:

    • To define minimal breast cancer and assess its clinical characteristics and prognosis.
    • To evaluate the survival rates associated with surgical intervention for these early-stage breast cancers.

    Main Methods:

    • Classification of breast lesions based on size (≤ 0.5 cm) and type (in situ, intraductal, microinvasive).
    • Statistical analysis of axillary lymph node involvement probability.
    • Review of survival data following surgical treatment.

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    Main Results:

    • Minimal breast cancer includes intraductal, intralobular, and microinvasive carcinomas.
    • These lesions have a ≤ 10% probability of axillary lymph node metastasis.
    • Surgical treatment yields a 5-year survival rate of 97% and a 10-year survival rate of 95%.

    Conclusions:

    • Surgical management of minimal breast cancer is highly effective.
    • Early detection and treatment of small breast lesions are crucial for favorable long-term survival outcomes.