Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Reflex Activity01:08

Reflex Activity

A reflex activity is an automatic, involuntary response to specific stimuli. It is a part of our survival mechanism, designed to protect us from potential harm. For example, when a bright light suddenly shines into our eyes, we instinctively close them or look away. This is a simple reflex activity orchestrated by the nervous system without conscious thought or effort.
A reflex exam is a diagnostic procedure performed by a healthcare professional to evaluate the functionality of a patient's...
Focusing of Light in the Eye01:16

Focusing of Light in the Eye

Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
Somatic Spinal Reflexes01:22

Somatic Spinal Reflexes

Somatic spinal reflexes are rapid, involuntary muscular responses to external stimuli that involve the somatic musculature and the spinal cord.
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identifying Risk-De-Escalating Markers in PREVENT-Defined Intermediate-Risk Older Adults: Insights From ASPREE.

Circulation. Population health and outcomes·2026
Same author

Long-term systolic blood pressure time in target and risk of cardiovascular events in older adults: a secondary analysis of the ASPREE cohort.

American journal of hypertension·2026
Same author

The effect of treating hearing loss with hearing aids on plasma biomarkers of Alzheimer's disease and related dementias.

Alzheimer's & dementia (Amsterdam, Netherlands)·2026
Same author

Association between eGFR and Disability-Free Survival in Older Adults Varies by Physical Function.

Kidney360·2026
Same author

The role of Lipoprotein(a) and oxidized phospholipids in modifying the effects of aspirin on major cardiovascular events and bleeding in the ASPirin in Reducing Events in the Elderly (ASPREE) randomized clinical trial: Statistical analysis plan.

medRxiv : the preprint server for health sciences·2026
Same author

Sepsis risk associated with clonal hematopoiesis of indeterminate potential (CHIP): a secondary analysis of the ASPREE trial.

Leukemia·2026

Related Experiment Video

Updated: Jul 14, 2026

Three Dimensional Vestibular Ocular Reflex Testing Using a Six Degrees of Freedom Motion Platform
10:12

Three Dimensional Vestibular Ocular Reflex Testing Using a Six Degrees of Freedom Motion Platform

Published on: May 23, 2013

Nonuniformity in the von Bezold-Jarisch reflex.

Lauren M Salo1, Robyn L Woods, Colin R Anderson

  • 1Howard Florey Institute, University of Melbourne, Victoria, 3010, Australia.

American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
|June 15, 2007
PubMed
Summary

The von Bezold-Jarisch reflex (BJR) often excites cardiac sympathetic nerve activity (CSNA) while inhibiting other sympathetic pathways. These divergent responses are primarily mediated by vagal nerves.

More Related Videos

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition
07:45

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition

Published on: July 21, 2020

Quantification of Visual Feature Selectivity of the Optokinetic Reflex in Mice
09:28

Quantification of Visual Feature Selectivity of the Optokinetic Reflex in Mice

Published on: June 23, 2023

Related Experiment Videos

Last Updated: Jul 14, 2026

Three Dimensional Vestibular Ocular Reflex Testing Using a Six Degrees of Freedom Motion Platform
10:12

Three Dimensional Vestibular Ocular Reflex Testing Using a Six Degrees of Freedom Motion Platform

Published on: May 23, 2013

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition
07:45

Assessing Binocular Central Visual Field and Binocular Eye Movements in a Dichoptic Viewing Condition

Published on: July 21, 2020

Quantification of Visual Feature Selectivity of the Optokinetic Reflex in Mice
09:28

Quantification of Visual Feature Selectivity of the Optokinetic Reflex in Mice

Published on: June 23, 2023

Area of Science:

  • Cardiovascular Physiology
  • Autonomic Nervous System Regulation

Background:

  • The von Bezold-Jarisch reflex (BJR) is a vagally mediated reflex affecting heart rate and respiration.
  • Previous studies have not systematically compared cardiac sympathetic nerve activity (CSNA) with vasomotor activity during the BJR.

Purpose of the Study:

  • To systematically compare CSNA and lumbar sympathetic nerve activity (LSNA) during the BJR.
  • To elucidate the role of vagal nerves in mediating divergent sympathetic responses during the BJR.

Main Methods:

  • In anesthetized rats, CSNA and LSNA were measured simultaneously during BJR activation by phenylbiguanide injection.
  • Responses were analyzed using normalized cumulative sums, with interventions including methyl atropine and vagotomy.

Main Results:

  • The BJR consistently reduced LSNA and heartbeats, often with a non-outweighing excitatory rebound.
  • CSNA was frequently excited during the BJR, with net excitation observed in most rats.
  • Vagotomy significantly reduced both excitatory and inhibitory LSNA and CSNA responses.

Conclusions:

  • CSNA is often excited during the BJR, contrasting with vasomotor inhibition.
  • Divergent responses occur simultaneously in cardiac vagal, cardiac sympathetic, and vasomotor pathways.
  • The vagi are the primary mediators of these divergent BJR responses.