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The role of TNFalpha in ulcerative colitis

Bruce E Sands1, Gilaad G Kaplan

  • 1Gastrointestinal Unit, Center for the Study of Inflammatory Bowel Diseases, and MGH Crohn's and Colitis Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA. bsands@partners.org

Journal of Clinical Pharmacology
|June 15, 2007
PubMed
Summary

Standard ulcerative colitis treatments often fail, necessitating colectomy for 20-30% of patients. Targeting tumor necrosis factor alpha (TNFalpha) with biologic therapies shows promise for treating this inflammatory bowel disease effectively.

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