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Efficacy of Monascus purpureus Went rice on lowering lipid ratios in hypercholesterolemic patients

Chien-Fang Huang¹, Tsai-Chung Li, Cheng-Chieh Lin

¹Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan, Republic of China.

European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology

|June 15, 2007

Abstract

Background:

Several lipid ratios may be predictors of coronary artery disease risk. We assessed the efficacy of Monascus purpureus Went rice (red yeast rice) on lowering lipid ratios.

Method And Results:

We evaluated 79 hypercholesterolemic patients (aged 23-65 years) who received a twice-daily dose of either red yeast rice or a placebo at 600 mg for 8 weeks. The 8-week treatment with red yeast rice showed significantly greater reduction than the placebo treatment in low-density lipoprotein cholesterol levels, total cholesterol/high-density lipoprotein cholesterol, low-density lipoprotein cholesterol/high-density lipoprotein cholesterol and apolipoprotein B/apolipoprotein A-I ratios.

Conclusions:

Red yeast rice can reduce lipid ratios in hypercholesterolemic patients.

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