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Evaluation of coronary stents and stenoses at different heart rates with dual source spiral CT (DSCT)
Michael M Lell1, Christoph Panknin, Roya Saleh
1Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA. Michael.Lell@idr.imed.uni-erlangen.de
Insights
Dual-source computed tomography (DSCT) effectively visualizes coronary arteries and stents up to 120 bpm without motion artifacts. This advanced CT imaging offers superior quality for evaluating coronary artery disease, even at higher heart rates.
Area of Science:
- Cardiovascular imaging
- Medical physics
- Radiology
Background:
- Evaluating coronary arteries at high heart rates and with coronary stents is challenging with current CT technology.
- Dual-source computed tomography (DSCT) offers high temporal resolution (83 ms), potentially overcoming heart rate limitations.
Purpose of the Study:
- To assess the efficacy of DSCT in visualizing coronary arteries and stents under simulated high heart rates and motion.
- To evaluate image quality and measurement accuracy of DSCT for coronary artery stenosis and in-stent evaluation.
Main Methods:
- Simulated cardiac motion using a robotic device with vessel phantoms (2-4 mm diameter) containing 50% stenosis or stents.
- DSCT scans performed at simulated heart rates from 50-120 bpm.
- Analysis of motion artifacts, lumen diameter measurements, and heart rate dependence of errors.
Main Results:
- Coronary stenoses and stents were visualized without motion artifacts up to 120 bpm.
- Image quality was comparable between static and dynamic (50-120 bpm) scans.
- Low errors for normal/stenotic lumen measurements (1-2%), but higher for in-stent measurements (27-32%).
Conclusions:
- DSCT enables clear depiction of coronary stents across a wide range of simulated heart rates without motion artifacts.
- Image quality achieved with DSCT surpasses previous CT scanner generations for coronary artery evaluation.
Objectives:
Evaluation of coronary arteries at higher heart rates and in the presence of coronary stents remains problematic. The utilization of dual source computed tomography (DSCT) might improve the visualization of the coronary arteries under these conditions by imaging at a temporal resolution of 83 milliseconds, independent of heart rate.
Materials And Methods:
Vessel phantoms (diameter 2-4 mm) were attached to a robotic device to simulate cardiac motion and scanned with a DSCT system. The phantoms had either inserts leading to 50% stenosis or carried stents. Images were evaluated for motion artifacts and measurements of the normal, stenotic, and in-stent lumen at different heart rates (50-120 bpm) were performed. Quantile regression analysis was performed to investigate heart rate dependence of the measurement errors.
Results:
Visualization of the stenoses and stents was possible without motion artifacts at heart rates of up to 120 bpm. Image quality was similar for the static (0 bpm) and the dynamic (50-120 bpm) scans. Errors for diameter measurements of the vessel lumen and the stenotic lumen were low (3-mm vessel: 1-2%), but considerable for in-stent diameter measurements (3-mm stent: 27-32%). A window/level setting of 1500/300 Hounsfield units was more favorable for stent evaluation. No heart rate dependence was found.
Conclusions:
Depiction of coronary stents with DSCT is possible across a large range of simulated heart rates without motion artifacts and with image quality superior to that of previous generations of CT scanners.
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