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Related Experiment Videos

Bronchopulmonary foregut malformations. A unifying etiological concept.

K B Heithoff, S M Sane, H J Williams

    AJR. American Journal of Roentgenology
    |January 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

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    Congenital bronchopulmonary foregut malformations often involve the left lower lobe or right lung, with most patients presenting in early infancy. Surgical intervention is typically curative for these rare developmental anomalies.

    Area of Science:

    • Pediatric Surgery
    • Thoracic Surgery
    • Congenital Malformations

    Background:

    • Congenital bronchopulmonary foregut malformations (CBPFMs) are rare developmental anomalies.
    • These malformations arise from a common embryologic origin, leading to diverse presentations.

    Observation:

    • A review of 29 cases identified CBPFMs most commonly affecting the left lower lobe or entire right lung.
    • The cardioesophageal junction was the most frequent site of communication (83%).
    • Most patients (60%) presented within the first eight months of life, with a higher incidence in females.

    Findings:

    • Chronic cough, recurrent pneumonias, and respiratory distress were common clinical manifestations.
    • Esophagography proved to be the most effective diagnostic tool (82%).

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  • Microscopic examination revealed fistulas resembling esophageal, bronchial, or combined tissues.

    • Implications:

    • Surgical treatment was curative in most cases, with pre-operative deaths often linked to associated anomalies.
    • Understanding the embryologic basis aids in diagnosing and managing these complex malformations.
    • CBPFMs encompass a spectrum including sequestrations, gastroesophageal communications, diverticula, and duplication cysts.