Related Experiment Video
Updated: Jul 14, 2026

COVID-19 Seroprevalence Test for IgG Antibody Levels Among Healthy Donors Across Different Pandemic Phases in Jeddah
Published on: June 24, 2025
Bordetella pertussis infection in a highly vaccinated population in Saudi Arabia, 1996-2004
Jaffar A Al-Tawfiq1, Abbas AbuKhamsin
1Division of Internal Medicine Specialty Services, Dhahran Health Center, Saudi Aramco Medical Services Organization, Saudi Aramco, Dhahran, Saudi Arabia. jaffar.tawfiq@aramco.com <jaffar.tawfiq@aramco.com>
Objectives:
The objective of this study was to describe the features and presentations of Bordetella pertussis infection at Saudi Aramco Medical Services Organization (SAMSO) in Saudi Arabia.
Methods:
This is a retrospective analysis of the reported cases of B. pertussis from January 1996 to December 2004.
Results:
During the study period, there were a total of 156 confirmed cases of B. pertussis infection. There were 88 males and 68 females, with male to female ratio of 1.3:1. Most (n=81; 52%) of the patients were less than six months of age. A large number (n=71; 45.5%) of patients were reported in 2003; 26.8% (n=19) were between 10-19 years and 22.5% (n=16) were >/=20 years of age. Of all the patients, 65 (42%) patients were hospitalized for a median of five days (range: 2-21 days). Of the total cases, 47 (30%) patients were fully vaccinated (>/=3 doses), 48 (30%) had not received any dose of vaccine, 33 (21%) had received one dose and six (3.8%) had received two doses. The vaccination status was not known for 22 (14%) patients. However, many of the infected infants were too young to have been eligible for vaccine. A total of 81 patients were less than six months of age and of those 58% (n=47) did not receive any doses, 39.5% (n=32) received one dose and 2.5% (n=2) received two doses.
Conclusion:
In this sample of cases of whooping cough arising in the highly vaccinated population of Saudi Arabia, the overwhelming majority of cases were infants less than six months of age and older adults.
Insights
This study on Bordetella pertussis (whooping cough) in Saudi Arabia found most cases were in infants under six months. Older adults were also significantly affected, highlighting vulnerabilities in a highly vaccinated population.
Area of Science:
- Infectious Diseases
- Pediatrics
- Epidemiology
Background:
- Pertussis, commonly known as whooping cough, remains a significant public health concern globally.
- Vaccination strategies aim to control pertussis transmission, but breakthrough infections can occur.
- Understanding the epidemiology of pertussis in specific regions is crucial for targeted public health interventions.
Purpose of the Study:
- To characterize the clinical features and demographic patterns of Bordetella pertussis infections.
- To analyze presentation and outcomes of pertussis cases within the Saudi Aramco Medical Services Organization (SAMSO) in Saudi Arabia.
- To identify specific age groups most affected by pertussis in this population.
Main Methods:
- A retrospective analysis was conducted on confirmed Bordetella pertussis cases.
- Data were collected from January 1996 to December 2004.
- Patient demographics, vaccination status, and clinical outcomes were reviewed.
Main Results:
- 156 confirmed cases of Bordetella pertussis were identified.
- The majority of cases (52%) were infants under six months of age.
- Hospitalization was required for 42% of patients, with a median stay of five days. Vaccination status varied, with a notable proportion of unvaccinated infants.
Conclusions:
- Infants under six months and older adults represent the most affected groups for whooping cough in this Saudi Arabian cohort.
- The findings underscore the importance of continued surveillance and vaccination efforts, particularly for vulnerable age groups.
- Pertussis poses a risk even in populations with high vaccination coverage.
Related Concept Videos
Vaccinations
Respiratory Syncytial Virus Disease
Inhalation Anthrax
Diphtheria
Smallpox
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
